Provitamin B5 aids the thickening of hair and is often compounded into shampoos and conditioners. It benefits the hair by increasing luster, moisture retention, and increased elasticity. The B Complex vitamins all have good results when used in hair and skin care products.
Panthenol (also called pantothenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms, it is quickly oxidized to pantothenic acid. It is a viscous transparent liquid at room temperature. Panthenol is used in pharmaceutical and cosmetic products as a moisturizer and to improve wound healing.
D-panthenol
| |
Names | |
---|---|
Preferred IUPAC name
2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide | |
Other names
| |
Identifiers | |
3D model (JSmol)
|
|
3DMet | |
1724945, 1724947 R | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.036.839 |
EC Number |
|
KEGG | |
MeSH | dexpanthenol |
PubChem CID
|
|
RTECS number |
|
UNII |
|
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C9H19NO4 | |
Molar mass | 205.254 g·mol−1 |
Appearance | Highly viscous, colourless liquid |
Density | 1.2 g mL−1 (at 20 °C) |
Melting point | 66 to 69 °C (151 to 156 °F; 339 to 342 K)[contradictory] |
Boiling point | 118 to 120 °C (244 to 248 °F; 391 to 393 K) at 2.7 Pa |
log P | −0.989 |
Acidity (pKa) | 13.033 |
Basicity (pKb) | 0.964 |
Chiral rotation ([α]D)
|
+29° to +30° |
Refractive index (nD)
|
1.499 |
Pharmacology | |
A11HA30 (WHO) D03AX03 (WHO), S01XA12 (WHO) | |
Hazards | |
NFPA 704 (fire diamond) | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
|
10,100 mg kg−1 (intraperitoneal, mouse); 15,000 mg kg−1 (oral, mouse) |
Related compounds | |
Related compounds
|
|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|