Homosalate is an organic compound used in some sunscreens. It is made by the Fischer–Speier esterification of salicylic acid and 3,3,5-trimethylcyclohexanol, the latter being a hydrogenated derivative of isophorone. Contained in 45% of U.S. sunscreens, it is used as a chemical UV filter. The salicylic acid portion of the molecule absorbs ultraviolet rays with a wavelength from 295 nm to 315 nm, protecting the skin from sun damage. The hydrophobic trimethyl cyclohexyl group provides greasiness that prevents it from dissolving in water.

Homosalate

Names
IUPAC name 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate
Other names Homosalate
Identifiers
CAS Number	118-56-9 Y
3D model (JSmol)	Interactive image
ChemSpider	8059 Y
ECHA InfoCard	100.003.874
KEGG	D04450 Y
PubChem CID	8362
UNII	V06SV4M95S Y
CompTox Dashboard (EPA)	DTXSID1026241
InChI InChI=1S/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3 Y Key: WSSJONWNBBTCMG-UHFFFAOYSA-N Y InChI=1/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3 Key: WSSJONWNBBTCMG-UHFFFAOYAJ
SMILES O=C(OC1CC(CC(C1)(C)C)C)c2ccccc2O
Properties
Chemical formula	C16H22O3
Molar mass	262.349 g·mol−1
Density	1.05 g/cm3 (20 °C)
Melting point	< -20 °C
Boiling point	181–185 °C (358–365 °F; 454–458 K)
Solubility in water	0.4 mg/L
Hazards
Flash point	171 °C (340 °F; 444 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references