The Benefits of N-Hydroxysuccinimide in Skincare

Skincare is a topic that has gained significant attention in recent years, with individuals becoming increasingly conscious of the appearance and health of their skin. One key ingredient that has garnered interest in the skincare world is N-Hydroxysuccinimide (NHS). This compound is commonly found in cosmetics and beauty products, particularly in eye creams, due to its potential benefits in reducing dark circles and inflammation under the eyes. In this comprehensive guide, we will explore the various functions and safety measures associated with N-Hydroxysuccinimide, as well as recommended products that contain this ingredient.

The Functions of N-Hydroxysuccinimide

N-Hydroxysuccinimide is an acidic ester that plays a crucial role in cosmetics and beauty products. It is primarily used in eye creams to activate the elimination of blood-originated pigments responsible for dark color and inflammation that causes under-eye circles. When applied topically, N-Hydroxysuccinimide helps render iron soluble, facilitating its natural elimination. This process is particularly beneficial in reducing the accumulation of hemoglobin and its colored degradation products, such as biliverdin, bilirubin, and iron, which contribute to the formation of infra-orbital shadows. By addressing these underlying factors, N-Hydroxysuccinimide aids in brightening the under-eye area and reducing the appearance of dark circles.

Safety Measures and Side Effects

While N-Hydroxysuccinimide is a commonly used ingredient in skincare products, it is important to consider its safety measures and potential side effects. Although limited research specifically focuses on N-Hydroxysuccinimide, it is known to be slightly acidic and can act as an irritant to the skin, eyes, and mucous membranes. As with any skincare ingredient, it is recommended to perform a patch test before using products containing N-Hydroxysuccinimide, especially for individuals with sensitive skin. If any adverse reactions occur, such as redness, itching, or irritation, it is advised to discontinue use and consult a dermatologist.

Recommended Products with N-Hydroxysuccinimide

Several of Reviva’s products harness the potential benefits of N-Hydroxysuccinimide. Here are some notable recommendations:

1. Firming Eye Serum with Alpha Lipoic Acid, Vitamin C Ester & DMAEReviva’s Firming Eye Serum with Alpha Lipoic Acid, Vitamin C Ester & DMAE – it helps reduce the appearance of eye-area wrinkles, puffiness and dark circles as you decrease future visible signs of aging.
2. Reviva’s  Under Eye Dark Circle Serum – a breakthrough formula that helps reduce the appearance of severe under-eye discoloration, dark circles, and puffiness. It features DMAE, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hyaluronic Acid, N-Hydroxysuccinamide, Chrysin, Caffeine, Niacinamide, and Magnesium Ascorbyl Phosphate

These eye products offer options for individuals seeking skincare solutions that target under-eye concerns.

Scientific Evidence Supporting the Efficacy of N-Hydroxysuccinimide in Skincare

To understand the efficacy of N-Hydroxysuccinimide in skincare, it is important to explore the scientific evidence backing its benefits. While research on this specific ingredient may be limited, studies have demonstrated its potential effectiveness in several key areas.

1. Reduction of Dark Circles and Inflammation

N-Hydroxysuccinimide has been found to activate the elimination of blood-originated pigments responsible for dark color and inflammation under the eyes. This process helps address the accumulation of hemoglobin and its degradation products, such as biliverdin, bilirubin, and iron, which contribute to the formation of under-eye shadows. By rendering iron soluble, N-Hydroxysuccinimide aids in the natural elimination of these pigments, resulting in reduced dark circles and inflammation.

2. Brightening and Enhancing Skin Tone

One of the notable benefits of N-Hydroxysuccinimide is its potential to brighten the skin and improve overall skin tone. By targeting the underlying factors that contribute to dark circles and pigmentation, N-Hydroxysuccinimide helps restore a more even and radiant complexion. This brightening effect can enhance the overall appearance of the skin and promote a more youthful look.

3. Supporting the Epidermal Barrier

Studies have shown that N-Hydroxysuccinimide can contribute to the improvement of the epidermal barrier. It has been found to upregulate the expression of genes involved in maintaining a healthy skin barrier, such as Aquaporin 3 (AQP3), Filaggrin (FLG), caspase 14, and keratin 10. By strengthening the epidermal barrier, N-Hydroxysuccinimide helps protect the skin from external aggressors and enhances its ability to retain moisture, resulting in improved skin health and resilience.

4. Reduction of Sensory Discomfort

N-Hydroxysuccinimide has been shown to reduce sensory discomfort associated with sensitive skin. It can alleviate the stinging sensation and inflammation resulting from heat exposure, contact with specific substances like capsaicin, and mechanical stress. By modulating the activity of factors involved in the inflammatory response and sensory perception, N-Hydroxysuccinimide helps promote a more comfortable and soothing skincare experience for individuals with sensitive skin.

The Importance of Patch Testing and Individual Sensitivities

When incorporating any new skincare product into your routine, including those containing N-Hydroxysuccinimide, it is crucial to perform a patch test. Patch testing involves applying a small amount of the product to a discreet area of skin, such as the inner forearm, and monitoring for any adverse reactions over a period of 24 to 48 hours. This precautionary measure helps identify potential sensitivities or allergies to specific ingredients, allowing individuals to make informed decisions about product suitability.

It is important to note that individual sensitivities can vary, and what works well for one person may not yield the same results for another. Therefore, it is advisable to consult a dermatologist or skincare professional who can provide personalized recommendations based on your skin type, concerns, and sensitivities.

Conclusion

N-Hydroxysuccinimide is a promising ingredient in skincare products, particularly in eye creams targeting under-eye concerns. Its ability to address dark circles, inflammation, and sensory discomfort makes it an appealing choice for individuals seeking effective solutions for their skincare needs. While further research is needed to fully understand the potential benefits and optimal usage of N-Hydroxysuccinimide, the existing scientific evidence suggests its efficacy in improving the appearance and health of the skin. By considering the recommended products and incorporating patch testing into your skincare routine, you can make informed choices to achieve healthier, more vibrant skin. Remember, skincare is a journey, and finding the right products that work for you may require experimentation and consultation with skincare professionals.